What I took issue with was the interpretation of the data below (Figure 1) as evidence of a rise in perinatal mortality among home births. Early in the post, Tuteur's one-line take-home-message was that...

The death toll of homebirth in Colorado is enormous and RISING!

**the first point is the one we should all be concerned about**, not the second which is my focus here. For more details, do read Tuteur's post over at the Skeptical OB and her other posts for links to more data.

So what does the data say?

**Figure 1**: Compiled by Tuteur from here and similar sources. Note these are women seeing midwives

*prior to birth*. For example, according to Tuteur the 799 in 2009 comes from "the 639 women who received midwifery care exclusively + the 160 women transferred to the hospital either before or after labor began."

So are those numbers rising?

**Figure 2**: The perinatal mortality rates from above, produced by the script below.

Clearly it looks like they are, but how should we interpret them? The answer depends on the question, and here we're interested in primarily one thing:

*. So is this evidence of increasing risk? To answer that, lets compare whether or not this apparent increase is real or perhaps just due to "random chance." We can do this quite easily in R (see the script at the bottom of this post) to see if these numbers look statistically different from one another using the chi-squared test chisq.test()in R.*

**risk**To do a two-group comparison, we can compare totals for the first two years with the totals for the last two years. Doing so gives...

Comparing each of the four years separately givesPearson's Chi-squared test with Yates' continuity correction X-squared = 0.2729, df = 1,p-value = 0.6014

So what does it all mean? We interpret the p-values as the probability that we would see these kinds of differences from chance alone. That is, in both cases it seems a little bit more likely than not that this apparent trend is really just "random chance." Typically we want p-values much closer to zero to rule out chance alone, therefore (statistically) there is noPearson's Chi-squared test X-squared = 0.8375, df = 3,p-value = 0.8405

*clear*increase in perinatal mortality rates.

Importantly, this is all based upon (1) just these data and (2) just the chi-squared test. Furthermore "no evidence for an increase" is a different claim than "there is no increase" -- so more data or a better statistical analysis might give a different result. For example, this is a time series and not four independent groups so focusing on their increasing order would require a somewhat different approach. All that said, these large p-values make me doubt a more appropriate statistical test would give any meaningfully different results for these data.

The take home message here is that having data like these available allows the public to answer some of these very important questions. Data like these belong in the public arena and organizations like MANA (Midwives Alliance of North America) should be quick to share it instead of keeping it from the public and their critics (as seems to be the case).

### R Code:

# Colorado Licensed Homebirth Midwives # Year, Patients at the start of labor (N), Perinatal Deaths (PD) Year=c(2006,2007,2008,2009); N = c(642, 696, 806, 799); PD = c(5,5,7,9); # Lump into two groups Yr = c(sum(Year[1:2]),sum(Year[3:4]))/2; n = c(sum(N[1:2]),sum(N[3:4])); pd = c(sum(PD[1:2]),sum(PD[3:4])); # Compute perinatal mortality rate. pd/n; # for each group, or mean(pmr); # lumped together. # Simple Chi-squared with continuity correction (by default in R) # p near 0 means statistically different, p near 1 means not. chisq.test(rbind(n-pd,pd)); # <-- corrected version. chisq.test(rbind(N-PD,PD)); # <-- corrected version. # For details of the chisq.test() function, see... ?chisq.test ## the help file or this link. # Plot the data plot(Year, PD/N*1000, pch=19, cex=2, cex.lab=1.4, ylim=c(0,15), ylab="Perinatal Deaths per 1000 (CO)");

## 2 comments:

Perhaps Dr. Tuteur was going back further in her analysis. The 2010 Sunset Review of DEMs also provides these perinatal mortality figures:

2004 4.7 per 1,000 births

2005 1.6 per 1,000 births

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