Gene regulation in mammalian cells: a complex democracy?

Monday, April 20, 2009 at 9:25 PM Bookmark and Share

[From Sandwalk]

A (perhaps oversold?) press release entitled "International team cracks mammalian gene control code" is making the rounds, and while maybe a bit overreaching it looks pretty interesting!

For more details, check out this a blurb from Nature Genetics: "FANTOM studies networks in cells: Systems biology boosted by RNA-sequencing consortium" by Heidi Ledford. You can also read the abstracts at the links below (abstracts only - the articles aren't freely available online).

Publication Links:

  1. The FANTOM Consortium and the Riken Omics Science Center, The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics (2009) doi:10.1038/ng.375
  2. Taft, R. J. et al. Tiny RNAs associated with transcription start sites in animals. Nature Genetics (2009) doi:10.1038/ng.312
  3. Faulkner, G. J. et al. The regulated retrotransposon transcriptome of mammalian cells. Nature Genetics (2009) doi:10.1038/ng.368


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